Yinherb Factory Supplier 98% Pure Polypeptide CAS 151126-32-8 Pramlintide Acetate Pramlintide for Research CAS NO.151126-32-8

Yinherb Supply 98% pure polypeptide cas 151126-32-8 Pramlintide Acetate Pramlintide
Name:Pramlintide Acetate
Cas No: 151126-32-8
Formula: C171H267N51O53S2
Molecular:3949.38
Pramlintide: KCNTATCATQRLANFLVHSSNNFGPILPPTNVGSNTY-(NH2)
Amylin:       KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-(NH2)
Rat amylin:  KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY-(NH2
Purity:98%
Appearance: white powder
Source: synthetic
Also know as Pramlintide acetate,Triproamylin,Symlin,Amylin (human) ,
Pramlintide, Pramlintide acetate [USAN],187887-46-3,196078-30-5.
Purity:98%
Source: synthetic
Appearance: White Lyophilized Powder
Minimum Order Quantity: 1 g
Brand Name: Yinherb
Test Method: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below-18° C. 

What is Pramlintide Acetate
Pramlintide (Symlin) is a relatively new injectable drug for  diabetes (both type 1 and 2), developed by Amylin  Pharmaceuticals (now a wholly owned subsidiary of AstraZeneca )Pramlintide is sold as an acetate salt.
Pramlintide is an analogue of  amylin ,a small peptide hormone that is released into the bloodstream by the β-cells of the pancreas along with insulin, after a meal.Like insulin, amylin is completely absent in individuals with Type I diabetes.

Pramlintide Acetate Benefits
Reduction in glycated hemoglobin and weight loss have been shown in insulin-treated patients with type 2 diabetes taking pramlintide as an adjunctive therapy.
By augmenting endogenous amylin, pramlintide aids in the cellular absorption and regulation of blood glucose by slowing gastric emptying, promoting satiety via hypothalamic receptors (different receptors than for GLP-1), and inhibiting inappropriate secretion of glucagon, a catabolic hormone that opposes the effects of insulin and amylin. Pramlintide also has effects in raising the acute first-phase insulin response threshold following a meal.

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