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Home > Products >  MK-677

MK-677 CAS NO.159752-10-0

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  • Min.Order: 10 Gram
  • Payment Terms: L/C,D/A,D/P,T/T,Western Union,MoneyGram
  • Product Details


  • MK-677
  • Ibutamoren
  • 159752-10-0

Quick Details

  • ProName: MK-677
  • CasNo: 159752-10-0
  • Molecular Formula: C28H40N4O8S2
  • Appearance: White fine powder
  • Application: Applicated in body building sarms.
  • DeliveryTime: 5-7days after you make payment by cour...
  • PackAge: 1kg/foil bag, 25kgs/drum
  • Port: Xi'an, Beijing, Shanghai
  • ProductionCapacity: 5 Kilogram/Week
  • Purity: 99.89%
  • Storage: Store at room temperature or cooler, i...
  • Transportation: We can ship out within 5 days after yo...
  • LimitNum: 10 Gram


Xi'an Yinherb Bio-Tech Co., Ltd was founded in 2009, We have more than 10 experienced doctors and scientists and professional managers, specializing in Nootropics, Sarms and Peptides researching and developing, and become the leader manufacturer on all kinds of nootropics powder, we guarantted the every batch quality and give you test report along with order, we always believe "quality is firstly, service is secondly, price is thirdly ", so must build with every customer in an enjoyable business relationship!
You are buying = Our Products + Our Service:
1,Quality is our culture ,strict QC/QA systems under GMP factory.
2,Fast and safe delivery with secure and discreet shipment.
3,With us, your money is in safe as well as your business.It's our promise to you!
4,For whatever questions about us or our products you may have, do let us know and you can be assured we reply you in details with 24 hours and to your satisfaction.
5,Warmly welcome your visit in our company if available.




MK-677 Ibutamoren Basic Info:

Product: MK-677 Ibutamoren 

Synonms: MK-677, MK-0677, L-163,191, 2-Amino-2-methyl-N-[1-(1-methylsulfonylspiro[2H-indole-3,4′-piperidine]-1′-yl)-1-oxo-3-(phenylmethoxy)propan-2-yl]propanamide

Specification: 99%
Mesh size: 80 Mesh
CAS: 159752-10-0
MF :  C28H40N4O8S2
MW : 624.77 g/mol
Purity: 99.0%
Appearance: White Powder
Minimum Order Quantity: 1 g
Brand Name: Yinherb
Test Method: HPLC
Item Specifications Results
Assay(HPLC) 98.0%~102.0% 99.4%
Appearance Off-white fine powder Complies
Identification Positive Reaction Complies
Melting point 224.0~227.0℃ 224.0~226.0℃
Ash ≤0.1% 0.08%
Loss on drying ≤0.5% 0.11%
Residue on ignition ≤0.1% 0.06%
Related substance ≤1.0% 0.75%
Chloride ≤50ppm Complies
Sulphate/Barium salt ≤60ppm Complies
Oxalate Pass Complies
Fe ≤5ppm Complies
As ≤50ppm Complies
Heavy metals ≤1ppm Complies



What is MK-677 Ibutamoren 

Ibutamoren is a white crystalline powder, also known as MK-677, MK-0677, and L-163,191. When people talk ibutamoren, they are referring to ibutamoren mesylate whose unique CAS number is 159752-10-0, while ibutamoren base with CAS number 159634-47-6. Ibutamoren mesylate has better stability and bioavailability than ibutamoren base. Therefore, if not specified, ibutamoren in this article means Ibutamoren mesylate, but MK-677 is a more well-known name to the market.
Ibutamoren mesylate (MK-677), based on Wikipedia, is really a potent, lengthy-acting, and selective agonist from the ghrelin/growth hormones secretagogue receptor (GHSR) along with a growth hormones secretagogue, resembling the development hormone (GH)-stimulating action from the endogenous hormone ghrelin. It is in the powder form, and also you don’t need to inject. MK-677 has been shown to improve the release of, and produces sustained increases in plasma amounts of several the body’s hormones including GH and blood insulin-like growth factor 1 (IGF-1), but without having affected cortisol levels.


MK-677 Ibutamoren Benefit:

Ibutamoren MK-677 was made to fight against such conditions as muscle wasting, weight problems and brittle bones. It had been also targeted to treat hip fractures with senior patients. As with every SARMS, MK-677 is non-steroidal and it is non-toxic towards the liver.
Probably the most noticeable result of MK-677 is elevated body fat oxidation and lean muscle mass gains.
It’s presently under development as a potential strategy to reduce amounts of these hormones, such as with children or grownups with growth hormones deficiency, and scientific testing on people have proven it to improve both muscle tissue and bone mineral density, which makes it an encouraging therapy to treat frailty within the seniors. Additionally, it alters metabolic process of body fat and thus might have application in treating weight problems.
Other possible advantages of ibutamoren MK-677 are connected with enhanced sleep, enhanced complexion, and rise in levels of energy, increase nitrogen retention, increase strength as well as an enhanced feeling of well-being. Additionally, some studies also claim that an elevated defense mechanisms response was triggered by ibutamoren (Mk-677), meaning it enhances the defense system to some degree.
Ibutamoren and growth hormone
The advantages of Growth Hormones on metabolic process and lean muscle mass are indisputable. Growth Hormones, also called Human growth hormone (Hgh) has got the key benefits as below:
Human growth hormone encourages and boosts the synthesis of new protein tissue, such as with muscle recovery or repair. This is one way new muscle is made.
Current research indicates its participation within the metabolic process of body fat and its conversion to energy sources. Tests were carried out in overweight people, and medical use in dealing with weight problems was proven beyond any doubt. Some pros used GH as a means of maintaining and growing lean mass while going on a diet for a long time.
It enhances the sleeping pattern, and creates less unintentional awakenings and betters REM-stage sleep.
Human growth hormone produces more energy
It might improve performance
It develops more powerful bones
Enhances the standard and time period of heart and renal system
All sorts of these benefits that be provided with a single ibutamoren component itself.

MK-677 Ibutamoren Dosage:

In healthy male adults, MK 677 works better than GHRH, generating an average peak GH concentration of 22.1μg/L after an oral dose of 25mg. Results have been confirmed from doses between 5-25mgs each day and dose dependent results can be expected. Larger doses, over 50mgs, happen to be reported by a few, however we don’t see the necessity to go crazy for it.

MK-677 Ibutamoren Function & Application:

Ibutamoren MK-677 is a nonpeptide spiropiperidine and it is functionally indistinguishable in vitro as well as in vivo from the GHRP-6. However, ibutamoren stimulates GH release via a pituitary and hypothalamic receptors (not the same as the GH-delivering hormone receptors), and has the capacity to sustain GH plasma levels and IGF1 release without having affected endogenous cortisol.
Growth hormones pulse intensity could be elevated through 4 possible ways:
Growing GHRH release (growth hormones releasing hormone).
Increasing GHRH signaling in somatotrophs from the anterior anterior pituitary gland.
Reducing somatostatin release (somatostatin turns off GH release).
Suppressing somatostatin receptor signaling.
Ibutamoren MK-677 was shown to function through all of these four mechanisms. After ingestion, Growth Hormones (GH) was proven to improve dose dependently, at doses beginning at 5 mg (mgs) each day.




Custom clearance service:

1) By Express:
Normally there is no specical need for the recipient to clear the customs. If the customs has an objection,our rich experienced and peofessional group will help you clear the customs. We can guarantee th shipment 100%.
2) By Air and by Sea:
Our company will cooperate with the recipient to provide relevant file and information in the customs clearance procedure.


Delivery Service:

We can ship out within 5 days after you make payment if it have stock at Lab, We always send all order by DHL, UPS, TNT, FedEx, EMS and other courier with door-door service, take 5 – 7 business days to your door!



Carton: 1kg, 2kg, 5kg with Foil bag inside, or as customer's requirment;

Drum: 10kg, 15kg, 25kg with food grade PE nag inside.




Shipping Terms
By Express By Air By sea

Suitable for ≤ 50kg   

Faster 5-7days              

High Cost                

Door to Door              

Easy Pick Up Goods

Suitable for ≥ 50kg   

Fastest: 1-2 days               

High Cost                

Airport to Airport      

Pick Up Goods by Customer             

Suitable for ≥ 500kg   

Fast: 15-30 days               

Low Cost                

Port to Port           

Pick Up Goods by Customer


Payment terms Western Union
Wire Transfer


Q1: Can i get some samples 
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments 
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Paypal.
Q3: How to confirm the Product Quality before placing orders 
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4:What’s your MOQ 
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5: How about delivery leadtime 
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6:Is there a discount 
A:Different quantity has different discount.
Q7: How do you treat quality complaint 
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

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