Compound 7P Basic Info:
Product Name: Compound 7
CAS No.: 1890208-58-8
Reaxys Registry Number: 29568294
Molecular Formula: C22H23N3O5S
Appearance: White fine powder
Molecular Weight: 441.508
Storage: Store in cool & dry place, Keep away from strong light and heat.
Shelf Life: 24Months when properly stored.
Grade: Food grade/Medicine/Injection grade
|
Item |
Specifications |
Results |
|
Assay(HPLC) |
98.0%~102.0% |
98.9% |
|
Appearance |
Off-white powder |
Complies |
|
Identification |
IR |
Complies |
|
Melting point |
156.0~160.0℃ |
157.0~158.0℃ |
|
Loss on drying |
≤0.5% |
0.11% |
|
Residue on ignition |
≤0.1% |
0.06% |
|
Related substance |
≤1.0% |
0.75% |
|
Heavy metals |
≤10ppm |
Complies |
What is Compound 7P
Compound 7p was developed as one in series of compounds with the aim of identifying dual-acting thromboxane receptor antagonist/synthase inhibitors . In fact compound 7p shows selectivity for prostaglandin I2 synthase (PTGIS, CYP8A1) over thromboxane synthase (CYP5A1).
Compound 7P Benefit:
Axon regeneration after injury in the central nervous system is hampered in part because if an age-dependent decline in the intrinsic axon growth potential, and one of the strategies to stimulate axon growth in injured neurons involves pharmacological manipulation of implicated signaling pathways.
Here we report phenotypic cell-based screen of chemical libraries and structure-activity-guided optimization that resulted in the identification of compound 7p which promotes neurite outgrowth of cultured primary neurons derived from the hippocampus, cerebral cortex, and retina.
In an animal model of optic nerve injury, compound 7p was shown to induce growth of GAP-43 positive axons, indicating that the in vitro neurite outgrowth activity of compound 7p translates into stimulation of axon regeneration in vivo. Further optimization of compound 7p and elucidation of the mechanisms by which it elicits axon regeneration in vivo will provide a rational basis for future efforts to enhance treatment strategies.
Compound 7P Function & Application:
1. Repare the danage head nerve.
2.here we report phenotypic cell-based screen of chemical libraries and structure-activity-guided optimization that resulted in the identification of compound 7p which promotes neurite outgrowth of cultured primary neurons derived from the hippocampus, cerebral cortex, and retina. in an animal model of optic nerve injury, compound 7p was shown to induce growth of gap-43 positive axons, indicating that the in vitro neurite outgrowth activity of compound 7p translates into stimulation of axon regeneration in vivo.
Custom clearance service:
1) By Express:
Normally there is no specical need for the recipient to clear the customs. If the customs has an objection,our rich experienced and peofessional group will help you clear the customs. We can guarantee th shipment 100%.
2) By Air and by Sea:
Our company will cooperate with the recipient to provide relevant file and information in the customs clearance procedure.
Delivery Service:
We can ship out within 5 days after you make payment if it have stock at Lab, We always send all order by DHL, UPS, TNT, FedEx, EMS and other courier with door-door service, take 5 – 7 business days to your door!
Packing:
Carton: 1kg, 2kg, 5kg with Foil bag inside, or as customer's requirment;
Drum: 10kg, 15kg, 25kg with food grade PE nag inside.
Delivery:
|
Shipping Terms |
|
By Express |
By Air |
By sea |
|
Suitable for ≤ 50kg
Faster 5-7days
High Cost
Door to Door
Easy Pick Up Goods
|
Suitable for ≥ 50kg
Fastest: 1-2 days
High Cost
Airport to Airport
Pick Up Goods by Customer
|
Suitable for ≥ 500kg
Fast: 15-30 days
Low Cost
Port to Port
Pick Up Goods by Customer
|
Payment:
|
Payment terms |
Western Union |
|
Moneygram |
|
PayPal |
|
Wire Transfer |
|
Bitcoin |
Q1: Can i get some samples
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, or Paypal or Escrow(Alibaba).
Q3: How to confirm the Product Quality before placing orders
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4:What’s your MOQ
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5: How about delivery leadtime
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6:Is there a discount
A:Different quantity has different discount.
Q7: How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
China (Mainland)
Premiumsupplier 
