NSI-189 Freebase Nootropics powder CAS NO.1270138-40-3

 

 

 

NSI-189 Freebase Basic Info:

Item	Specifications	Results
Assay(HPLC)	98.0%~102.0%	98.9%
Appearance	Off-white crystalline powder	Complies
Identification	IR	Complies
Melting point	156.0~160.0℃	157.0~158.0℃
Loss on drying	≤0.5%	0.11%
Residue on ignition	≤0.1%	0.06%
Related substance	≤1.0%	0.75%
Heavy metals	≤10ppm	Complies

 

Real Point:

 

 

What is NSI-189 Freebase

NSI-189 is neurogenic and nootropic research agent that was developed from nicotinamide and pyrazine. Randomized controlled trials have shown that it stimulates neurogenesis or neuronal cell production in the brain. In animal studies, it has also been shown to increase the volume of hippocampus by 20% thereby reversing behavioral symptoms of depression. Such studies have shown that it may be an effective treatment for depression. It is also thought to be a promising treatment for other condition including post-traumatic stress disorder (PTSD), Alzheimer’s disease and age-related cognitive problems.

 

NSI-189 Freebase Benefit:

NSI-189 Freebase Function & Application:

NSI-189 significantly improved behavioral responses that are associated with depression . In humans it may counter hippocampal atrophy which is seen in disorders such as MDD, reversing their symptoms. A phase 1B randomized, double-blind, placebo-controlled, multiple-dose escalation study conducted over a 28 day period showed behavioral efficacy in 24 patients who were orally administered NSI-189 . The efficacy measurements showed a clinically meaningful reduction in cognitive and depressive symptoms across all measures, and appeared to persist over time during follow up for the efficacy assessments which included the Clinical Global Impression – Improvement (CGI-I), Montgomery-Aserb Depression Rating Scale (MADRS), Cognitive and Physical Functioning Questionnaire (CPFQ, and the Symptoms of Depression Questionnaire (SDQ).

 

 

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Packing:

Carton: 1kg, 2kg, 5kg with Foil bag inside, or as customer's requirment;

Drum: 10kg, 15kg, 25kg with food grade PE nag inside.

 

 

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